Bone Abstracts

Aim: The aim of this study is evaluating of body composition and frequency of sarcopenia in women depending on age.Materials and methods: We have examined 8637 women aged 20–89 years (mean age – 56.7±0.14 years; mean height – 162.5±0.07 cm; mean weight – 73.5±0.16 kg). The patients were divided into two groups depending on age: 20–24 (n=143), 25–29 (n=209), 30–34 (n=271), 35&#15...

The aim of the research: To investigate the effect of combined calcium and vitamin D therapy (calcium 1000 mg, vitamin D 400 IU) on 25(OH)D level and concentration of bone turnover markers in patients with systemic postmenopausal osteoporosis.Methods: 20 women with systemic postmenopausal osteoporosis were examined. The average age of the patients was (63.0 (59.00; 68.00)) years. The study was performed during winter season to exclude the influence of se...

In the recent years, worldwide the FRAX algorithm is used more extensively to estimate the risk of fragility fractures. Since 2009, the Ukrainian Scientific Medical Centre on Osteoporosis has been extensively using the FRAX algorithm to estimate the fragility fracture risk.The aim of the study was to establish the normative data for the Austrian model of FRAX algorithm. We examined 3405 women aged 40–89. For the statistical analysis of results the S...

Aim of research: To determine the prevalence of hyperuricemia affecting the Ukrainian men in relation to the bone mineral density and TBS.Object of research: The Ukrainian men (n=132), age of the examined patients –from 50 to 80 years. Average age of examined patients was 58.2±1.3 years. According to the levels of uric acid in the blood serum, all patients were divided in four quartiles.Methods of research: Uric ...

Introduction: Optimal 25(OH)D serum level is very important for bone health and calcium–phosphate homeostasis as well as for optimal function of many organs and tissues. The consequences of vitamin D deficiency are mineralization defects, which may lead to osteomalacia in the long-term, and muscle weakness, causing falls and fractures.Objectives: The aim of the research is to determine the frequency of vitamin D deficiency and it’s influence on...

Background: Epidermolysis bullosa (BE) is a group of inherited diseases that are characterized by skin and mucosal fragility and blister formation. The various complications such as malnutrition, anemia, growth retardation, esophageal stenosis and deformities may develop. Low bone mass and fractures recognized as complications of generalized forms of EB.Presenting problem: In the Ukrainian medical center of osteoporosis there were examined nine children ...

The aim of the research was to determine the efficacy of alfacalcidol (Alpha D3 Teva) in the treatment of women with postmenopausal osteoporosis and vitamin D deficiency.Methods: 20 women with systemic postmenopausal osteoporosis were examined. All patients had vitamin D deficiency (the average level of 25(OH)D in blood serum was (37.16 (24.9, 45.1)) nmol/l). Alfacalcidol was prescribed for 12 month in doses 1 μg. duration of observation was 12 mont...

Perinatal infections appreciably defines the level’s of the neonatal deseases and death rates. The systemic inflammatory response syndrome at the infections can promote the softening of the bone’s tissue in pregnant women and their fetuses.Objectives: Definition of the connection of the level’s calcium-regulated hormones and bone tissue remodeling marker’s in blood at 32 (II) healthy and 48 (I) pregnant women with perinatal infections...

The aim of the study was to evaluate the peculiarities of body composition in postmenopausal women depending on bone mineral density (BMD).Materials and methods: We’ve examined 8882 women aged 20–89 years (mean age – 56.7±0.14 years; mean height – 162.5±0.07 cm; mean weight – 73.5±0.16 kg). Anthropometric measures were performed in 80 postmenopausal women aged 40–82 years (mean age – 63.53±1.08 years...

Objectives: Evaluation of influence the structural and functional condition of bone tissue on caries intensity in adolescents living with deficient of fluoride in drinking water (<0.4 mg/l).Methods: It was examined 200 school children (12 and 15 years old) living in Transcarpathian region.Oral examination was done to determine caries intensity in the subjects (DMFT-index). Bone quality was determined using quantitative ultrasou...